Volume 5, Issue 1 (March 2018)                   J. Food Qual. Hazards Control 2018, 5(1): 17-23 | Back to browse issues page

XML Print


Research Center for Food Hygiene and Safety, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , eslami_g2000@yahoo.com
Abstract:   (551 Views)
Background: Toxoplasmosis is one of the most prevalent parasitic infections among humans and animals which caused by Toxoplasma gondii. This study was carried out to detection and identification of T. gondii in pregnant women population of Urmia, Iran.
Methods: This cross-sectional study was done from August 2015 to March 2016. Totally, 620 pregnant women referred to the urban and rural healthcare centers of Urmia were studied. IgG and IgM specific for T. gondii were assessed by enzyme-linked immunosorbent assay. The demographic and risk factors data were collected by questionnaires. All included women completed the consent letter of agreement. The identification of T. gondii was performed using nested Polymerase Chain Reaction. The statistical analysis was done using SPSS 16.0.
Results: Out of 620 pregnant women, 114 (18.4%) had specific IgG and three (0.5%) had specific IgM for T. gondii. Statistical analysis showed significant relation between the IgG level and age (p<0.05). We did not find any significant relation (p>0.05) between the level of ­T. gondii specific antibodies with career, education, and vegetable and meat consumption habits. Molecular identification of T. gondii showed type I in isolates obtained from three newborns of IgM-positive mothers.
Conclusion: In order to prevent of the disease in newborns, screening of pregnant women and healthcare education are suggested.

DOI:
10.29252/jfqhc.5.1.17
Full-Text [PDF 528 kb]   (319 Downloads)    
Type of Study: Original article | Subject: Special
Received: 17/12/03 | Accepted: 18/02/09 | Published: 18/03/16

References
1. Akhlaghi L., Ghasemi A., Hadighi R., Tabatabaie F. (2014). Study of seroprevalence and risk factors for Toxoplasma gondii among pregnant women in Karaj township of Alborz province, 2013. Journal of Entomology and Zoology Studies. 2: 217-219.
2. Alameh T., Tavangar F. (2002). Frequency of congenital toxoplasmosis and early neonatal morbidity in Shahid Beheshty Medical Center, Isfahan. Iranian Journal of Obstetrics, Gynecology and Infertility. 5: 6-13. [Persian fulltext with English abstract]
3. Anvari Tafti M., Ghafourzadeh M. (2014). Seroepidemiology of Toxoplasma infection in pregnant women in Yazd in 2012. Toloo-e-Behdasht. 13: 116-125. [Persian fulltext with English abstract]
4. Arbabi M., Talari S.A., Asmar M. (1997). Seroepidemiology of toxoplasmosis in Kashan, 1993. Feyz Journals of Kashan University of Medical Sciences. 1: 29-37. [Persian fulltext with English abstract]
5. Boughattas S., Ben-Abdallah R., Siala E., Ben-Abda I., Souissi O., Aoun K., Bouratbine A. (2011). Tunisian Toxoplasma gondii strains genotyping by the use of AK69 marker. Parasites and Vectors. 4: 167. [DOI:10.1186/1756-3305-4-167]
6. Boughattas S., Bouratbine A. (2015). Genetic Characterization of Toxoplasma gondii isolated from chicken meats in Tunisia. Journal of Food Quality and Hazards Control. 2: 97-100.
7. Brown A.S., Schaefer C.A., Quesenberry C.P. Jr., Liu L., Babulas V.P., Susser E.S. (2005). Maternal exposure to toxoplasmosis and risk of schizophrenia in adult offspring. American Journal of Psychiatry. 162: 767-773. [DOI:10.1176/appi.ajp.162.4.767]
8. Buchy P., Follezou J.Y., Lien T.X., An T.T., Tram L.T., Tri D.V., Cuong N.M., Glaziou P., Chien B.T. (2003). Serological study of toxoplasmosis in Vietnam in a population of drug users (Ho Chi Minh city) and pregnant women (Nha Trang). Bulletin de la Societe de Pathologie Exotique (1990). 96: 46-47. [French fulltext with English abstract]
9. Chaudhry S.A., Gad N., Koren G. (2014). Toxoplasmosis and pregnancy. Canadian Family Physician. 60: 334-336.
10. Ertug S., Okyay P., Turkmen M., Yuksel H. (2005). Seroprevalence and risk factors for Toxoplasma infection among pregnant women in Aydin province, Turkey. BMC Public Health. 5: 66. [DOI:10.1186/1471-2458-5-66]
11. Fallah M., Matini M., Taherkhani H., Rabiee S., Hajiloei M. (2006). Seroepidemiology of toxoplasmosis among pregnant women in Hamadan city. Scientific Journal of Hamadan University of Medical Sciences. 13: 33-37. [Persian fulltext with English abstract]
12. Fallah M., Rabiee S., Matini M., Taherkhani H. (2008). Seroepidemiology of toxoplasmosis in primigravida women in Hamadan, Islamic Republic of Iran, 2004. Eastern Mediterranean Health Journal. 14: 163-171.
13. Fazaeli A., Carter P.E., Darde M.L., Pennington T.H. (2000). Molecular typing of Toxoplasma gondii strains by GRA6 gene sequence analysis. International Journal for Parasitology. 30: 637-642. [DOI:10.1016/S0020-7519(00)00036-9]
14. Firouz Z.E., Kaboosi H., Faghih Nasiri A., Tabatabaie S.S., Golhasani-Keshtan F., Zaboli F. (2014). A comparative serological study of toxoplasmosis in pregnant women by CLIA and ELISA methods in Chalus City Iran. Iranian Red Crescent Medical Journal. 16: e15115.
15. Ghasemloo H., Ghomashlooyan M., Hooshyar H. (2014). Seroprevalence of Toxoplasma gondii infection among pregnant women admitted at Shahid Akbar Abadi hospital, Tehran, Iran, 2010-2013. Journal of Medical Microbiology and Infectious Diseases. 1: 16-19.
16. Hajimohammadi B., Eslami G., Oryan A., Zohourtabar A., Pourmirzaei Tafti H., Moghaddam Ahmadi M. (2014a). Molecular identification of Sarcocystis hominis in native cattle of central Iran: a case report. Tropical Biomedicine. 31: 183-186.
17. Hajimohammadi B., Moghadam Ahmadi M., Eslami G., Oryan A., Dehghani A., Zohourtabar A. (2014b). Molecular method development to identify foodborne Sarcocystis hominis in raw beef commercial hamburger. International Journal of Enteric Pathogens. 2: 1-3. [DOI:10.17795/ijep21139]
18. Hajsoleimani F., Ataeian A., Nourian A.A., Mazloomzadeh S. (2012). Seroprevalence of Toxoplasma gondii in pregnant women and bioassay of IgM positive cases in Zanjan, Northwest of Iran. Iranian Journal of Parasitology. 7: 82-86.
19. Iqbal J., Khalid N. (2007). Detection of acute Toxoplasma gondii infection in early pregnancy by IgG-avidity and PCR analysis. Journal of Medical Microbiology. 56: 1495-1499. [DOI:10.1099/jmm.0.47260-0]
20. Khurana S., Bagga R., Aggarwal A., Lyngdoh V.; Shivapriya, Diddi K., Malla N. (2010). Serological screening for antenatal Toxoplasma infection in India. Indian Journal of Medical Microbiology. 28: 143-146. [DOI:10.4103/0255-0857.62492]
21. Lopes-Mori F.M., Mitsuka-Breganó R., Capobiango J.D., Inoue I.T., Reiche E.M., Morimoto H.K., Casella A.M., Bittencourt L.H., Freire R.L., Navarro I.T. (2011). Programs for control of congenital toxoplasmosis. Revista da Associação Médica Brasileira. 57: 594-599. [DOI:10.1590/S0104-42302011000500021]
22. Maldonado Y.A., Read J.S. (2017). Diagnosis, treatment, and prevention of congenital toxoplasmosis in the United States. Pediatrics. 139: e20163860. [DOI:10.1542/peds.2016-3860]
23. Nowakowska D., Stray‐Pedersen B., Śpiewak E., Sobala W., Małafiej E., Wilczyński J. (2006). Prevalence and estimated incidence of Toxoplasma infection among pregnant women in Poland: a decreasing trend in the younger population. Clinical Microbiology and Infection. 12: 913-917. [DOI:10.1111/j.1469-0691.2006.01513.x]
24. Ortega Y.R., Sterling C.R. (2018). Foodborne parasites. Springer, Switzerland. [DOI:10.1007/978-3-319-67664-7]
25. Panah A.S., Assadi M., Bahman Soufiani K., Barzegar G., Gharachorlou A., Emami Zeydi A. (2013). Seroprevalence of Toxoplasma gondii infection among pregnant women in Amol, Northern Iran. Life Science Journal. 10: 164-168.
26. Pashaie Naghadeh A., Dabirzadeh M., Davoodi T., Hashemi M. (2015). Seroepidemiology of toxoplasmose in pregnant women in Tabas city. Medical Laboratory Journal. 9: 119-126.
27. Porto A.M., Amorim M.M., Coelho I.C., Santos L.C. (2008). Serologic profile of toxoplasmosis in pregnant women attended at a teaching-hospital in Recife. Revista da Associação Médica Brasileira. 54: 242-248. [Portuguese fulltext with English abstract] [DOI:10.1590/S0104-42302008000300018]
28. Rai S.K., Shibata H., Sumi K., Rai G., Rai N., Manandhar R., Gurung G., Ono K., Uga S., Matsuoka A., Shrestha H.G., Matsumura T. (1998). Toxoplasma antibody prevalence in Nepalese pregnant women and women with bad obstetric history. Southeast Asian Journal of Tropical Medicine and Public Health. 29: 739-743.
29. Rasti S., Behrashi M., Bandepour M., Talebian A., Fatahian A., Kazemi B., Moosavi G. (2012). Incidence of toxoplasmosis in neonates and its complications. Journal of Shahid Sadoughi University Of Medical Sciences . 19: 578-585. [Persian fulltext with English abstract] [DOI:10.1016/S0020-7292(12)61773-1]
30. Razzak A.H., Wais S.A., Saeid A.Y. (2005). Toxoplasmosis: the innocent suspect of pregnancy wastage in Duhok, Iraq. Eastern Mediterranean Health Journal. 11: 625-632.
31. Roc M.L., Palacian M.P., Lomba E., Monforte M.L., Rebaje V., Revillo Pinilla M.J. (2010). Serologic diagnosis of congenital toxoplasmosis. Enfermedades Infecciosas y Microbiologia Clinica. 28: 517-519. [DOI:10.1016/j.eimc.2009.11.004]
32. Rosso F., Les J.T., Agudelo A., Villalobos C., Chaves J.A., Tunubala G.A., Messa A., Remington J.S., Montoya J.G. (2008). Prevalence of infection with Toxoplasma gondii among pregnant women in Cali, Colombia, South America. The American Journal of Tropical Medicine and Hygiene. 78: 504-508.
33. Saeedi M., Bakhshandeh Nosrat S., Ghaemi E., Hedayat Mofidi S.M., Kohsar F., Behnampour N. (2002). The prevalence of Toxoplasma antibodies in women during marriage consultation in Gorgan. Journal of Gorgan University of Medical Sciences. 4: 64-71. [Persian fulltext with English
34. Sharbatkhori M., Dadi Moghaddam Y., Pagheh A.S., Mohammadi R., Hedayat Mofidi H., Shojaee S. (2014). Seroprevalence of Toxoplasma gondii infections in pregnant women in Gorgan city, Golestan province, Northern Iran-2012. Iranian Journal of Parasitology. 9: 181-187.
35. Song K.J., Shin J.C., Shin H.J., Nam H.W. (2005). Seroprevalence of toxoplasmosis in Korean pregnant women. The Korean Journal of Parasitology. 43: 69-71. [DOI:10.3347/kjp.2005.43.2.69]
36. Tavasoli M., Ghorhbanzadegan M., Esmailnejad B., Mardani K., Hosseinzadeh S. (2012). Identification of Toxoplasma gondii strain in human and mouse in Urmia by PCR-RFLP. Pajouhesh-Va-Sazandegi. 25: 29-34. [Persian fulltext with English abstract]
37. Tavassoli M., Tabatabaei M., Javadi S.H., Esmaeilnejad B., Kazemnia A., Mardani K. (2010). Investigation on Toxoplasma gondii infection in domestic animals in Urmia by PCR and RFLP. Pajouhesh-Va-Sazandegi. 22: 64-70. [Persian fulltext with English abstract]