Volume 10, Issue 4 (December 2023)
J. Food Qual. Hazards Control 2023, 10(4): 189-198 |
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Nwankwo I, Anyaoha C, Nwabueze C, Nwobi O, Ibeachu C. Risk Assessment of Toxic Heavy Metals Concentration of Fish and Drinking Water in Nsukka Metropolis, South East, Nigeria. J. Food Qual. Hazards Control 2023; 10 (4) :189-198
URL: http://jfqhc.ssu.ac.ir/article-1-1164-en.html
URL: http://jfqhc.ssu.ac.ir/article-1-1164-en.html
Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Enugu State, Nigeria , innocent.nwankwo@unn.edu.ng
Abstract: (534 Views)
Background: Toxic Heavy Metals (THMs) threaten food safety and result in human poisonings. It seems to be few studies on THMs contamination in food chain in developing countries. Current investigation determine the concentration and health risk of arsenic (As), cadmium (Cd), lead (Pb), as well as mercury (Hg) in fish and water at Nsukka, Metropolis, Enugu state, Nigeria.
Methods: Forty eight samples; 24 (catfish and tilapia) fish and 24 (borehole, sachet, and bottled) water were randomly collected from two major markets and districts in Nsukka Metropolis and were evaluated for THMs using Atomic Absorption Spectrophotometer. The Estimated Daily Intake, Target Hazard Quotient, Hazard Index, and Cancer Risk (CR) were assessed as well.
Results: THMs analaysis showed that As, Cd, and Hg were at 100% and Pb being at 16% in all the fish samples while 12.5% of fish of exceeded the Hg Maximum Permissible Limit (MPL) of 0.050 mg/kg, that not statistically significant (p>0.05).On the other hand, based on the analysis of all water samples, Hg and As were detected at 100% rate, Cd at 58.3% while Pb was not identified. The values above the MPL appeared to be 9 (37.5%), 2 (8.3%), and 3(12.5%) for Hg, As, and Cd, respectively in water while not statistically significant (p>0.05). The mean value of Hg (0.06425 mg/kg) in roasted fish as well as Cd (0.0065 and 0.0105) mg/ml in tap and bottled water respectively surpassed the MPL although not statistically significant (p>0.05). The Estimated Daily Intake of THMs except Cd in fish were proved to be within the Provisional Tolerable Daily Intake in contrast with As and Cd in water. CR is present both in children and adults with CR value >1.
Conclusion: The finding of THMs in fish and water above the MPL is regarded as potential health risk for the consumers of such contaminated water and fish in the investigation scope.
DOI: 10.18502/jfqhc.10.4.14177
Methods: Forty eight samples; 24 (catfish and tilapia) fish and 24 (borehole, sachet, and bottled) water were randomly collected from two major markets and districts in Nsukka Metropolis and were evaluated for THMs using Atomic Absorption Spectrophotometer. The Estimated Daily Intake, Target Hazard Quotient, Hazard Index, and Cancer Risk (CR) were assessed as well.
Results: THMs analaysis showed that As, Cd, and Hg were at 100% and Pb being at 16% in all the fish samples while 12.5% of fish of exceeded the Hg Maximum Permissible Limit (MPL) of 0.050 mg/kg, that not statistically significant (p>0.05).On the other hand, based on the analysis of all water samples, Hg and As were detected at 100% rate, Cd at 58.3% while Pb was not identified. The values above the MPL appeared to be 9 (37.5%), 2 (8.3%), and 3(12.5%) for Hg, As, and Cd, respectively in water while not statistically significant (p>0.05). The mean value of Hg (0.06425 mg/kg) in roasted fish as well as Cd (0.0065 and 0.0105) mg/ml in tap and bottled water respectively surpassed the MPL although not statistically significant (p>0.05). The Estimated Daily Intake of THMs except Cd in fish were proved to be within the Provisional Tolerable Daily Intake in contrast with As and Cd in water. CR is present both in children and adults with CR value >1.
Conclusion: The finding of THMs in fish and water above the MPL is regarded as potential health risk for the consumers of such contaminated water and fish in the investigation scope.
DOI: 10.18502/jfqhc.10.4.14177
Type of Study: Original article |
Subject:
Special
Received: 22/12/09 | Accepted: 23/11/10 | Published: 23/12/30
Received: 22/12/09 | Accepted: 23/11/10 | Published: 23/12/30
References
1. Adeyeye S.A.O., Oyewole O.B. (2016). An overview of traditional fish smoking in Africa. Journal of Culinary Science and Technology. 14: 198-215. [DOI: 10.1080/15428052.2015. 1102785] [DOI:10.1080/15428052.2015.1102785]
2. Aloke C., Uzuegbu I.E., Ogbu P.N., Ugwuja E.L., Orinya O.F., Obasi I.O. (2019). Comparative assessment of heavy metals in drinking water sources from Enyigba community in Abakaliki local government area, Ebonyi state, Nigeria. African Journal of Environmental Science and Technology. 13: 149-154. [DOI: 10.5897/AJEST2018.2517] [DOI:10.5897/AJEST2018.2517]
3. Baby J., Raj J.S., Biby E.T., Sankarganesh P., Jeevitha M.V., Ajisha S.U., Rajan S.S. (2010). Toxic effect of heavy metals on aquatic environment. International Journal of Biological and Chemical Sciences. 4: 939-952. [DOI: 10.4314/ijbcs.v4i4.62976] [DOI:10.4314/ijbcs.v4i4.62976]
4. Bajwa B.S., Kumar S., Singh S., Sahoo S.K., Tripathi R.M. (2017). Uranium and other heavy toxic elements distribution in the drinking water samples of SW-Punjab, India. Journal of Radiation Research and Applied Sciences. 10: 13-19. [DOI: 10.1016/j.jrras.2015.01.002] [DOI:10.1016/j.jrras.2015.01.002]
5. Bawuro A.A., Voegborlo R.B., Adimado A.A. (2018). Bioaccumulation of heavy metals in some tissues of fish in lake Geriyo, Adamawa state, Nigeria. Journal of Environmental and Public Health. 2018: 1854892. [DOI: 10.1155/2018/1854892] [DOI:10.1155/2018/1854892] [PMID] [PMCID]
6. Bhattacharya P.T., Misra S.R., Hussain M. (2016). Nutritional aspects of essential trace elements in oral health and disease: an extensive review. Scientifica. 2016: 5464373. [DOI: 10.1155/2016/5464373] [DOI:10.1155/2016/5464373] [PMID] [PMCID]
7. Chakraborti D., Singh S.K., Rahman M.M., Dutta R.N., Mukherjee S.C., Pati S., Kar P.B. (2018). Groundwater arsenic contamination in the Ganga river basin: a future health danger. International Journal of Environmental Research and Public Health. 15: 180. [DOI: 10.3390/ijerph15020180] [DOI:10.3390/ijerph15020180] [PMID] [PMCID]
8. Chowdhury S., Mazumder M.A.J., Al-Attas O., Husain T. (2016). Heavy metals in drinking water: occurrences, implications, and future needs in developing countries. Science of the Total Environment. 569-570: 476-488. [DOI: 10.1016/j.scitotenv. 2016.06.166] [DOI:10.1016/j.scitotenv.2016.06.166] [PMID]
9. De Mattia G., Bravi M.C., Laurenti O., De Luca O., Palmeri A., Sabatucci A., Mendico G., Ghiselli A. (2004). Impairment of cell and plasma redox state in subjects professionally exposed to chromium. American Journal of Industrial Medicine. 46: 120-125. [DOI: 10.1002/ajim.20044] [DOI:10.1002/ajim.20044] [PMID]
10. Djedjibegovic J., Marjanovic A., Tahirovic D., Caklovica K., Turalic A., Lugusic A., Omeragic E., Sober M., Caklovica F. (2020). Heavy metals in commercial fish and seafood products and risk assessment in adult population in Bosnia and Herzegovina. Scientific Reports. 10: 13238. [DOI: 10.1038/s41598-020-70205-9] [DOI:10.1038/s41598-020-70205-9] [PMID] [PMCID]
11. Ekere N.R., Ihedioha J.N., Eze I.S., Agbazue V.E. (2014). Health risk assessment in relation to heavy metals in water sources in rural regions of South East Nigeria. International Journal of Physical Sciences. 9: 109-116. [DOI: 10.5897/IJPS2014.4125] [DOI:10.5897/IJPS2014.4125]
12. European Committee for Standardization (CEN). (2013). Foodstuffs. determination of elements and their chemical species.General considerations and specific requirements. (EN 13804:2013).
13. European Committee for Standardization (CEN). (2003). Foodstuffs - determination of trace elements - determination of lead, cadmium, zinc, copper and iron by atomic absorption spectrometry (AAS) after microwave digestion. (EN 14084:2003). URL: https://cdn.standards.iteh.ai/samples/13882/17b47550d2214056b08fe84311270885/SIST-EN-14084-2003.pdf.
14. European Committee for Standardization (CEN). (2014): Foodstuffs - determination of trace elements - pressure digestion. (EN 13805:2014). URL: https://nobelcert.com/DataFiles/FreeUpload/ EN%2013805-2014.pdf.
15. European Environment Agency., WHO Regional Office for Europe. (2002). Children's health and environment: a review of evidence. Official Publications of the European Communities, Luxembourg. URL: https://iris.who.int/bitstream/handle/10665/ 107338/ 9789291674121-eng.pdf?sequence=1.
16. Eze V.C., Ndife C.T., Muogbo M.O. (2021). Carcinogenic and non-carcinogenic health risk assessment of heavy metals in Njaba river, Imo state, Nigeria. Brazilian Journal of Analytical Chemistry. 8: 57-70. [DOI: 10.30744/brjac.2179-3425.AR-05-2021] [DOI:10.30744/brjac.2179-3425.AR-05-2021]
17. Hadiani M.R., Dezfooli-manesh S., Shoeibi S., Ziarati P., Mousavi Khaneghah A. (2015). Trace elements and heavy metals in mineral and bottled drinking waters on the Iranian market. Food Additives and Contaminants: Part B. 8: 18-24. [DOI: 10.1080/19393210. 2014.947526] [DOI:10.1080/19393210.2014.947526] [PMID]
18. Huseen H.M., Mohammed A.J. (2019). Heavy metals causing toxicity in fishes. Journal of Physics: Conference Series. 1294: 062028. [DOI: 10.1088/1742-6596/1294/6/062028] [DOI:10.1088/1742-6596/1294/6/062028]
19. Ihedioha J.N., Amu I.A., Ekere N.R., Okoye C.O.B. (2016). Levels of some trace metals (Pb, Cd and Ni) and their possible health risks from consumption of selected fish and shellfish from Nigerian markets. International Food Research Journal. 23: 2557-2563.
20. Kessler R. (2013). The minamata convention on mercury: a first step toward protecting future generations. Environmental Health Perspectives. 121: A304-a309. [DOI: 10.1289/ehp.121-A304] [DOI:10.1289/ehp.121-A304]
21. Khatri N., Tyagi S. (2015). Influences of natural and anthropogenic factors on surface and groundwater quality in rural and urban areas. Frontiers in Life Science. 8: 23-39. [DOI: 10.1080/21553769.2014.933716] [DOI:10.1080/21553769.2014.933716]
22. Lo Y.-C., Dooyema C.A., Neri A., Durant J., Jefferies T., Medina-Marino A., De Ravello L., Thoroughman D., Davis L., Dankoli R.S., Samson M.Y., Ibrahim L.M., et al. (2012). Childhood lead poisoning associated with gold ore processing: a village-level investigation-Zamfara state, Nigeria, October-November 2010. Environmental Health Perspectives. 120: 1450-1455. [DOI: 10.1289/ehp.1104793] [DOI:10.1289/ehp.1104793] [PMID] [PMCID]
23. Naseri K., Salmani F., Zeinali M., Zeinali T. (2021). Health risk assessment of Cd, Cr, Cu, Ni and Pb in the muscle, liver and gizzard of hen's marketed in East of Iran. Toxicology Reports. 8: 53-59. [DOI: 10.1016/j.toxrep.2020.12.012] [DOI:10.1016/j.toxrep.2020.12.012] [PMID] [PMCID]
24. National Geospatial-Intelligence Agency (NGIA). (2008). Nsukka, Nigeria. URL: https://geographic.org/geographic_names/ name.php? uni=-2810134&fid=4303&c=nigeria.Accessed 11 November 2022.
25. Naujokas M.F., Anderson B., Ahsan H., Aposhian H.V., Graziano J.H., Thompson C., Suk W.A.(2013). The broad scope of health effects from chronic arsenic exposure: update on a worldwide public health problem. Environmental Health Perspectives. 121: 295-302. [DOI: 10.1289/ehp.1205875] [DOI:10.1289/ehp.1205875] [PMID] [PMCID]
26. Njoga E.O., Ezenduka E.V., Ogbodo C.G., Ogbonna C.U., Jaja I.F., Ofomatah A.C., Okpala C.O.R. (2021). Detection, distribution and health risk assessment of toxic heavy metals/metalloids, arsenic, cadmium, and lead in goat carcasses processed for human consumption in south-eastern Nigeria. Foods. 10: 798. [DOI: 10.3390/foods10040798] [DOI:10.3390/foods10040798] [PMID] [PMCID]
27. Nwankwo I.O., Ezenduka E.V., Nwanta J.A., Ogugua A.J., Audu B.J. (2021). Prevalence of Campylobacter spp. and antibiotics resistant E. coli on poultry carcasses and handlers' hands at Ikpa slaughter, Nsukka, Nigeria. Notulae Scientia Biologicae. 13: 10866. [DOI: 10.15835/nsb13210866] [DOI:10.15835/nsb13210866]
28. Peng G., Pu Z., Chen F., Xu H., Cao X., Chen C.C., Wang J., Liao Y., Zhu X., Pan K. (2023). Metal leaching from plastics in the marine environment: an ignored role of biofilm. Environment International. 177: 107988. [DOI: 10.1016/j.envint.2023.107988] [DOI:10.1016/j.envint.2023.107988] [PMID]
29. Pipoyan D., Stepanyan S., Beglaryan M., Stepanyan S., Mendelsohn R., Deziel N.C. (2023). Health risks of heavy metals in food and their economic burden in Armenia. Environment International. 172: 107794. [DOI: 10.1016/j.envint.2023.107794] [DOI:10.1016/j.envint.2023.107794] [PMID]
30. Prakash Bansal O.M. (2020). Health risks of potentially toxic metals contaminated water. In: Kanayochukwu Nduka J., Nageeb Rashed M. (Editors). Heavy metal toxicity in public health. IntechOpen, London, United Kingdom. pp: 63-93. [DOI: 10.5772/intechopen. 92141] [DOI:10.5772/intechopen.92141]
31. Rajeshkumar S., Liu Y., Zhang X., Ravikumar B., Bai G., Li X. (2018). Studies on seasonal pollution of heavy metals in water, sediment, fish and oyster from the Meiliang bay of Taihu lake in China. Chemosphere. 191: 626-638. [DOI: 10.1016/j. chemosphere. 2017.10.078] [DOI:10.1016/j.chemosphere.2017.10.078] [PMID]
32. Ramachandran A., Krishnamurthy R.R., JayaprakashM., Balasubramanian M. (2018). Concentration of heavy metal in surface water and groundwater Adyar river basin, Chennai, Tamilnadu, India. IOSR Journal of Applied Geology and Geophysics. 6:29-35. [DOI: 10.9790/0990-0602022935]
33. Saha N., Rahman M.S., Ahmed M.B., Zhou J.L., Ngo H.H., Guo W. (2017). Industrial metal pollution in water and probabilistic assessment of human health risk. Journal of Environmental Management. 185: 70-78. [DOI: 10.1016/j.jenvman.2016.10.023] [DOI:10.1016/j.jenvman.2016.10.023] [PMID]
34. Saikat M., Arka J.C., Abu M.T., Talha B.E., Firzan N., Ameer K., Abubakr M.I., Mayeen U.K., Hamid O., Fahad A.A., Jesus S.-G. (2022). Impact of heavy metals on the environment and human health: novel therapeutic insights to counter the toxicity. Journal of King Saud University Science. 34: 101865. [DOI: 10.1016/j.jksus.2022.101865] [DOI:10.1016/j.jksus.2022.101865]
35. Salman S.A., Zeid S.A.M., Seleem E.-M.M., Abdel-Hafiz M.A. (2019). Soil characterization and heavy metal pollution assessment in Orabi farms, El Obour, Egypt. Bulletin of the National Research Centre. 43: 42. [DOI: 10.1186/s42269-019-0082-1] [DOI:10.1186/s42269-019-0082-1]
36. Sankhla M.S., Kumar R., Prasad L. (2020). Variation of chromium concentration in Yamuna river (Delhi) water due to change in temperature and humidity. Journal of Seybold Report. 15: 293-299.
37. Semu E., Tindwa H., Singh B.R. (2019). Heavy metals and organopesticides: ecotoxicology, health effects and mitigation options with emphasis on sub-saharan Africa. HSOA Journal of Toxicology: Current Research. 3: 010. [DOI: 10.24966/TCR-3735/100010] [DOI:10.24966/TCR-3735/100010]
38. Smith A.H., Lingas E.O., Rahman M. (2000). Contamination of drinking-water by arsenic in Bangladesh: a public health emergency. Bulletin of the World Health Organization. 78: 1093-1103.
39. Smitha P.G., Byrappa K., Ramaswamy S.N. (2007). Physico-chemical characteristics of water samples of Bantwal Taluk, south-western Karnataka, India. Journal of Environmental Biology. 28: 591-595.
40. Sonone S.S., Jadhav S., Sankhla M.S., Kumar R. (2021). Water contamination by heavy metals and their toxic effect on aquaculture and human health through food chain. Letters in Applied NanoBioScience. 10: 2148-2166. [DOI: 10.33263/ LIANBS102.21482166] [DOI:10.33263/LIANBS102.21482166]
41. Tangahu B.V., Abdullah S.R.S., Basri H., Idris M., Anuar N., Mukhlisin M. (2011). A review on heavy metals (As, Pb, and Hg) uptake by plants through phytoremediation. International Journal of Chemical Engineering. 2011: 939161.[DOI: 10.1155/2011/ 939161] [DOI:10.1155/2011/939161]
42. Tchounwou P.B., Yedjou C.G., Patlolla A.K., Sutton D.J. (2012). Heavy metal toxicity and the environment.Molecular, clinical and environmental toxicology. 1st edition. Springer Basel, Switzerland. [DOI: 10.1007/978-3-7643-8340-4_6] [DOI:10.1007/978-3-7643-8340-4_6] [PMID] [PMCID]
43. Ukachukwu L.K. (2012).Heavy metal concentrations in water, Clarias gariepinus and Tilapia guineensis from agodi lake inIbadan. MSc thesis department of environmental health sciences faculty of public health college of medicine University of Ibadan, Nigeria. pp: 1-178. URL: http://repository.ui.edu.ng/bitstream/123456789/ 766/1/UKACHUKWU%2C%20LINDA%20KELECHI.pdf.
44. United States Environmental Protection Agency (EPA). (2012). Edition of the drinking water standards and health advisories. EPA 822-S-12-001. United States Environmental Protection Agency, Washington, DC. URL: https://rais.ornl.gov/documents/ 2012_drinking_water.pdf.
45. United State Environment Protection Agency (EPA). (2021). Regional screening levels (RSLs) - generic tables. URL: https://www. epa.gov/ risk/ regional-screening-levels-rsls-generic-tables.
46. United State Environment Protection Agency (EPA). (2020). RSL calculator. URL: https://epa-prgs.ornl.gov/cgi-bin/chemicals/ csl_search. Accessed 18 January 2021.
47. U.S. Department of Health and Human Services., U.S. Department of Agriculture. (2015). 2015 - 2020 Dietary guidelines for Americans. 8th Edition. URL: https://health.gov/our-work/food-nutrition/previous-dietary-guidelines/2015. Accessed 24 February 2020.
48. Varsha G. (2013). Mammalian feces as bio-indicator of heavy metal contamination in Bikaner zoological garden, Rajasthan, India. Research Journal of Animal, Veterinary and Fishery Sciences. 1: 1-4.
49. Wongsasuluk P., Chotpantarat S., Siriwong W., Robson M. (2014). Heavy metal contamination and human health risk assessment in drinking water from shallow groundwater wells in an agricultural area in Ubon Ratchathani province, Thailand. Environmental Geochemistry and Health. 36: 169-182. [DOI: 10.1007/s10653-013-9537-8] [DOI:10.1007/s10653-013-9537-8] [PMID]
50. World Health Organization (WHO). (2003). Diet, nutrition and the prevention of chronic diseases. Joint WHO/FAO Expert Consultation, Geneva, Switzerland. pp: 54-59. URL: https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=b2b75a3c3f615277380936b54944da8736998e62. Accessed 17 February 2020.
51. World Health Organization (WHO). (2017). Guidelines for drinking-water quality. 4th edition. URL: https://iris.who.int/ bitstream/ handle/10665/254637/9789241549950-eng.pdf?sequence=1. Accessed 12 January 2020.
52. World Health Organization., Unicef. (2013). Progress on sanitation and drinking-water - 2013 update. WHO Press, Geneva, Switzerland. URL: file:///C:/Users/admin/Downloads/Progress% 20on% 20Sanitation%20and%20Drinking-Water%202013% 20Update.pdf.
53. Wu L., Yue W., Wu J., Cao C., Liu H., Teng Y. (2023). Metal-mining-induced sediment pollution presents a potential ecological risk and threat to human health across China: A meta-analysis. Journal of Environmental Management. 329: 117058. [DOI: 10.1016/j.jenvman.2022.117058] [DOI:10.1016/j.jenvman.2022.117058] [PMID]
54. Yakubu N.M. (2016). Assessment of heavy metals and polycyclic aromatic hydrocarbons in water, fish and sediments of rivers Niger and Benue confluence, in Lokoja, Kogi state, Central Nigeria. Msc thesis submitted in the department of pure and industrial chemistry, University of Nigeria, Nsukka.
55. Yang Y., Yanai R.D., Montesdeoca M., Driscoll C.T. (2017). Measuring mercury in wood: challenging but important. International Journal of Environmental Analytical Chemistry. 97: 456-467. [DOI: 10.1080/03067319.2017.1324852] [DOI:10.1080/03067319.2017.1324852]
56. Živković N., Takić L., Djordjević L., Djordjević A., Mladenović-Ranisavljević I., Golubović T., Božilov A. (2019). Concentrations of heavy metal cations and a health risk assessment of sediments and river surface water: a case study from a Serbian mine. Polish Journal of Environmental Studies. 28: 2009-2020. [DOI: 10.15244/pjoes/89986] [DOI:10.15244/pjoes/89986]
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