Volume 6, Issue 4 (December 2019)                   J. Food Qual. Hazards Control 2019, 6(4): 146-152 | Back to browse issues page

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Matsuo Y, Nakai K, Sakuma I, Akutsu K, Tatsuta N, Ishiyama M, et al . Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population. J. Food Qual. Hazards Control. 2019; 6 (4) :146-152
URL: http://jfqhc.ssu.ac.ir/article-1-631-en.html
Graduate School of Agriculture, Saga University, Saga, Japan , uenod@cc.saga-u.ac.jp
Abstract:   (2891 Views)
Background: Oily fish and their extracted oils may be a source of polychlorinated biphenyls (PCBs) which can induce toxic effects on the consumers. The main aim of this survey was estimation of PCBs intake through fish oil-derived dietary supplements and prescription drugs in the Japanese population.
Methods: PCBs levels were determined in 20 fish oil-derived dietary supplements and 6 oil-derived prescription drugs from the Japanese market using Gas Chromatography-Mass Spectrometry. Then, the daily exposure to PCBs was estimated. Data were statistically analyzed using JMP software suite.
Results: Totally, 17 of the 26 fish oil-derived products were contaminated with PCBs. The median PCB concentrations in the total set of fish oil-derived products was 2.2 ng/g oil wt. with a range of <MDL-720 ng/g oil wt. The average total daily intake of PCBs was estimated to be ranged from 770 to 2800 ng/day in the Japanese population.
Conclusion: PCBs intakes through fish oil-derived dietary supplements and prescription drugs in the Japanese adults were much lower than tolerable daily intake.

DOI: 10.18502/jfqhc.6.4.1992
Full-Text [PDF 482 kb]   (511 Downloads)    
Type of Study: Original article | Subject: Special
Received: 19/07/01 | Accepted: 19/11/15 | Published: 19/12/16

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